褰撳墠浣嶇疆: 棣栭〉 >> 姝ｆ枃
鍗楁搗鎵�棣栨瀹屾垚鏂戣妭瀵硅櫨鍗曠粏鑳?yōu)鍩哄洜鍥捐氨鏋勫?/h3>
榪戞棩錛屼腑鍥芥按浜х瀛︾爺絀墮櫌鍗楁搗姘翠駭鐮旂┒鎵�鏉庤繍涓滃崥澹瓑浜烘垚鍔熷畬鎴愭枒鑺傚铏懼崟緇嗚優(yōu)嫻嬪簭錛屾瀯寤轟簡(jiǎn)棣栦釜鏂戣妭瀵硅櫨鍗曠粏鑳?yōu)鍩哄洜鍥捐氨锛屼负瀵硅櫨鎶楅�嗘満鍒剁殑閬椾紶瑙ｆ瀽鎻愪緵浜?jiǎn)閲嶈鐞嗚Z緷鎹�傜浉鍏崇爺絀舵垚鏋滃彂琛ㄥ湪Frontiers in Immunology錛堛�婂厤鐤鍓嶆部銆嬶級(jí)涓?(Li Yundong, Zhou Falin, Yang Qibin, Jiang Song, Huang Jianhua, Yang Lishi, Ma Zhenhua and Jiang Shigui., Single-Cell Sequencing Reveals Types of Hepatopancreatic Cells and Haemocytes in Black Tiger Shrimp (Penaeus monodon) and Their Molecular Responses to Ammonia Stress. Front. Immunol. (2022) 13:883043.)銆?/p>
鍩轟簬緇嗚優(yōu)澶氭牱鍖栧姛鑳戒富瑕佺敱鍩哄洜椹卞姩鐨勭敓鐗╁鐗瑰緛錛屽崡嫻鋒墍鏂戣妭瀵硅櫨鍒涙柊鍥㈤槦鐜囧厛寮�灞曚簡(jiǎn)瀵硅櫨鐨勫崟緇嗚優(yōu)瑙ｇ鍜屽熀鍥犳祴搴忓伐浣溿�傞�氳繃涓嶆柇鐨勬懜绱㈠拰瀹為獙鏂規(guī)浼樺寲錛岃鍥㈤槦鎴愬姛紿佺牬浜?jiǎn)瀵硅檮』劸l囪В紱誨拰鍗曠粏鑳?yōu)鎮(zhèn)恫鍒跺鎶�鏈紝鍗曠粏鑳?yōu)鏍囪鎴悑z葷巼杈?5%浠ヤ笂錛屾崟鑾蜂簡(jiǎn)12712涓緇嗚優(yōu)鍜?1226涓倽鑳拌吅緇嗚優(yōu)錛屾祴寰?50 Gb鍩哄洜琛ㄨ揪鏁版嵁錛屽疄鐜頒簡(jiǎn)寰祦鎺ф妧鏈湪铏懼崟緇嗚優(yōu)嫻嬪簭涓殑搴旂敤錛岄嬈℃瀯寤轟簡(jiǎn)瀵硅櫨鑲濊儼鑵哄拰琛�娣嬪反鐨勫崟緇嗚優(yōu)鍩哄洜鍥捐氨錛岃В鏋愪簡(jiǎn)涓嶅悓緇嗚優(yōu)綾誨瀷瀵規(guī)皚鑳佽揩鍝嶅簲鐨勫垎瀛愭満鍒躲�?/p>
鍩轟簬鍩哄洜鏍囪灝嗙粏鑳?yōu)鎴愬姛鍒嗕?縐嶇粏鑳?yōu)绫痪煠锛尵l嗚優(yōu)鍙戣偛杞ㄨ抗棰勬祴鍙戠幇錛孒em4鍜孒em5緇嗚優(yōu)緹や綅浜庡彂鑲叉湯绔紝鏄緇嗚優(yōu)涓緝涓烘垚鐔熺殑鍏嶇柅緇嗚優(yōu)綾誨瀷錛岃�屼笖Hem4鏄綋娑插厤鐤殑涓昏鏁堝簲緇嗚優(yōu)緹わ紝鑳藉鍒嗘硨鎶楄弻鑲斤紝嬋�媧籶roPO緋葷粺銆傝倽鑳拌吅緇嗚優(yōu)瀛樺湪3縐嶆綔鍦ㄥ彂鑲茶礬寰勶紝Hep1鏄悎鎴愬縐嶆秷鍖栭叾鍜屽嚌闆嗙礌鐨勯噸瑕佺粏鑳?yōu)缇ゃ�傞壌瀹氬彂鐜癆MPs銆乸roPO鍜孏ST絳夊熀鍥犱笉浠呭彲浠ヤ綔涓洪壌瀹氳櫨緇嗚優(yōu)緹ょ殑鏍囪鍩哄洜錛岃�屼笖鍦ㄧ粏鑳?yōu)鍒嗗寲鍜屽姛鑳藉彲濉戞�т腑鍙戞尌鐫�閲嶈浣滅敤銆傝鐮旂┒棣栨鎴愬姛灝?0脳genomics緋葷粺搴旂敤浜庢棤鑴婃鍔ㄧ墿鐢插３綾葷爺絀訛紝鏋勫緩浜?jiǎn)姘}鑳佽揩涓嬭倽鑳拌吅鍜岃娣嬪反鐨勫崟緇嗚優(yōu)鍩哄洜杞綍鍥捐氨錛屾弿緇樹(shù)簡(jiǎn)铏懼厛澶╁厤鐤郴緇熷搴旀縺鍝嶅簲鐨勭粏鑳?yōu)鏈虹悊锛屼负瀵硅櫨鎶楅�嗘満鍒剁殑閬椾紶瑙ｆ瀽鎻愪緵浜?jiǎn)閲嶈鐞嗚Z緷鎹�?/p>
鍗楁搗鎵�涓婅堪鐮旂┒宸ヤ綔寰楀埌鍗楁柟嫻鋒磱縐戝涓庡伐紼嬪箍涓滅渷瀹為獙瀹わ紙騫垮窞錛夈�佹搗鍗楃渷宕栧窞婀劇瀛愬疄楠屽絳夌殑甯姪錛屼互鍙?qiáng)鍥藉畨檱嶇偣鐮斿彂璁″垝鈥滆摑鑹茬伯浠撶鎶�鍒涙柊鈥濅笓欏歸」鐩�佹枒鑺傚铏懼垱鏂板洟闃熼」鐩�佸箍涓滅渷闈掑勾鍩洪噾銆佹搗鍗楃渷闈掑勾鍩洪噾絳夌殑鏀寔銆?/p>
鍏ㄦ枃閾炬帴:https://doi.org/10.3389/fimmu.2022.883043
寰俊鎵竴鎵?br>鍒嗕韓鍒版湅鍙嬪湀
榪戞棩錛屼腑鍥芥按浜х瀛︾爺絀墮櫌鍗楁搗姘翠駭鐮旂┒鎵�鏉庤繍涓滃崥澹瓑浜烘垚鍔熷畬鎴愭枒鑺傚铏懼崟緇嗚優(yōu)嫻嬪簭錛屾瀯寤轟簡(jiǎn)棣栦釜鏂戣妭瀵硅櫨鍗曠粏鑳?yōu)鍩哄洜鍥捐氨锛屼负瀵硅櫨鎶楅�嗘満鍒剁殑閬椾紶瑙ｆ瀽鎻愪緵浜?jiǎn)閲嶈鐞嗚Z緷鎹�傜浉鍏崇爺絀舵垚鏋滃彂琛ㄥ湪Frontiers in Immunology錛堛�婂厤鐤鍓嶆部銆嬶級(jí)涓?(Li Yundong, Zhou Falin, Yang Qibin, Jiang Song, Huang Jianhua, Yang Lishi, Ma Zhenhua and Jiang Shigui., Single-Cell Sequencing Reveals Types of Hepatopancreatic Cells and Haemocytes in Black Tiger Shrimp (Penaeus monodon) and Their Molecular Responses to Ammonia Stress. Front. Immunol. (2022) 13:883043.)銆?/p>
鍩轟簬緇嗚優(yōu)澶氭牱鍖栧姛鑳戒富瑕佺敱鍩哄洜椹卞姩鐨勭敓鐗╁鐗瑰緛錛屽崡嫻鋒墍鏂戣妭瀵硅櫨鍒涙柊鍥㈤槦鐜囧厛寮�灞曚簡(jiǎn)瀵硅櫨鐨勫崟緇嗚優(yōu)瑙ｇ鍜屽熀鍥犳祴搴忓伐浣溿�傞�氳繃涓嶆柇鐨勬懜绱㈠拰瀹為獙鏂規(guī)浼樺寲錛岃鍥㈤槦鎴愬姛紿佺牬浜?jiǎn)瀵硅檮』劸l囪В紱誨拰鍗曠粏鑳?yōu)鎮(zhèn)恫鍒跺鎶�鏈紝鍗曠粏鑳?yōu)鏍囪鎴悑z葷巼杈?5%浠ヤ笂錛屾崟鑾蜂簡(jiǎn)12712涓緇嗚優(yōu)鍜?1226涓倽鑳拌吅緇嗚優(yōu)錛屾祴寰?50 Gb鍩哄洜琛ㄨ揪鏁版嵁錛屽疄鐜頒簡(jiǎn)寰祦鎺ф妧鏈湪铏懼崟緇嗚優(yōu)嫻嬪簭涓殑搴旂敤錛岄嬈℃瀯寤轟簡(jiǎn)瀵硅櫨鑲濊儼鑵哄拰琛�娣嬪反鐨勫崟緇嗚優(yōu)鍩哄洜鍥捐氨錛岃В鏋愪簡(jiǎn)涓嶅悓緇嗚優(yōu)綾誨瀷瀵規(guī)皚鑳佽揩鍝嶅簲鐨勫垎瀛愭満鍒躲�?/p>
鍩轟簬鍩哄洜鏍囪灝嗙粏鑳?yōu)鎴愬姛鍒嗕?縐嶇粏鑳?yōu)绫痪煠锛尵l嗚優(yōu)鍙戣偛杞ㄨ抗棰勬祴鍙戠幇錛孒em4鍜孒em5緇嗚優(yōu)緹や綅浜庡彂鑲叉湯绔紝鏄緇嗚優(yōu)涓緝涓烘垚鐔熺殑鍏嶇柅緇嗚優(yōu)綾誨瀷錛岃�屼笖Hem4鏄綋娑插厤鐤殑涓昏鏁堝簲緇嗚優(yōu)緹わ紝鑳藉鍒嗘硨鎶楄弻鑲斤紝嬋�媧籶roPO緋葷粺銆傝倽鑳拌吅緇嗚優(yōu)瀛樺湪3縐嶆綔鍦ㄥ彂鑲茶礬寰勶紝Hep1鏄悎鎴愬縐嶆秷鍖栭叾鍜屽嚌闆嗙礌鐨勯噸瑕佺粏鑳?yōu)缇ゃ�傞壌瀹氬彂鐜癆MPs銆乸roPO鍜孏ST絳夊熀鍥犱笉浠呭彲浠ヤ綔涓洪壌瀹氳櫨緇嗚優(yōu)緹ょ殑鏍囪鍩哄洜錛岃�屼笖鍦ㄧ粏鑳?yōu)鍒嗗寲鍜屽姛鑳藉彲濉戞�т腑鍙戞尌鐫�閲嶈浣滅敤銆傝鐮旂┒棣栨鎴愬姛灝?0脳genomics緋葷粺搴旂敤浜庢棤鑴婃鍔ㄧ墿鐢插３綾葷爺絀訛紝鏋勫緩浜?jiǎn)姘}鑳佽揩涓嬭倽鑳拌吅鍜岃娣嬪反鐨勫崟緇嗚優(yōu)鍩哄洜杞綍鍥捐氨錛屾弿緇樹(shù)簡(jiǎn)铏懼厛澶╁厤鐤郴緇熷搴旀縺鍝嶅簲鐨勭粏鑳?yōu)鏈虹悊锛屼负瀵硅櫨鎶楅�嗘満鍒剁殑閬椾紶瑙ｆ瀽鎻愪緵浜?jiǎn)閲嶈鐞嗚Z緷鎹�?/p>
鍗楁搗鎵�涓婅堪鐮旂┒宸ヤ綔寰楀埌鍗楁柟嫻鋒磱縐戝涓庡伐紼嬪箍涓滅渷瀹為獙瀹わ紙騫垮窞錛夈�佹搗鍗楃渷宕栧窞婀劇瀛愬疄楠屽絳夌殑甯姪錛屼互鍙?qiáng)鍥藉畨檱嶇偣鐮斿彂璁″垝鈥滆摑鑹茬伯浠撶鎶�鍒涙柊鈥濅笓欏歸」鐩�佹枒鑺傚铏懼垱鏂板洟闃熼」鐩�佸箍涓滅渷闈掑勾鍩洪噾銆佹搗鍗楃渷闈掑勾鍩洪噾絳夌殑鏀寔銆?/p>
鍏ㄦ枃閾炬帴:https://doi.org/10.3389/fimmu.2022.883043
綺ゅ叕緗戝畨澶?4010502001742鍙?/a>